The light aircraft was carrying eight people, including the pilot and two crew members, a doctor, a nurse, a flight medic and an American and a Canadian passenger, according to local radio reports, citing airport officials.
It was not clear whether the passengers were being airlifted for treatment of the viral disease.
“Unfortunately, no passenger survived the accident,” the Manila International Airport Authority said in a statement, adding that the runway had been closed and an investigation was underway.
The Research Institute for Tropical Medicine, the Philippine agency at the forefront of combating the disease, uses the same aircraft from a Philippine charter flight company called Lionair to transport supplies to the medical workers on the front line in the provinces across the archipelago, the government said.
Lionair, a Philippine-based firm, is separate from Lion Air, the Indonesian carrier that is one of the world’s fastest-growing airlines. The budget carrier has racked up several major accidents, including the fatal crash in 2018 of a 737 jetliner.
Senator Richard Gordon, the head of the Philippine Red Cross, said that medical teams had been dispatched to the airport to respond to the crash involving Flight 5880.
“Eight passengers — consisting of a flight medic, a nurse, doctor, three flight crew, one patient and its companion were onboard,” he said. “The airplane caught fire and exploded as it was taking off the NAIA runway 24,” he added, referring to the Ninoy Aquino International Airport. “The fire was enormous.”
Lionair Inc. flies charter flights and has contracts with the government. It operates air ambulances too and is helping the government in its anti-coronavirus program, transporting medical supplies.
In September a light aircraft also operated by the charter company crashed in Laguna, a suburban province just south of Manila, killing nine people aboard.